2'-Deoxyuridine
- Name2'-Deoxyuridine
- CAS951-78-0
- Purity99%
Product Details
Chinese factory supply 2'-Deoxyuridine 951-78-0 in stock with high standard
- Molecular Formula:C9H12N2O5
- Molecular Weight:228.205
- Appearance/Colour:White crystalline powder
- Melting Point:167-169 °C(lit.)
- Refractive Index:52 ° (C=1, 1mol/L NaOH)
- Boiling Point:370.01°C (rough estimate)
- PKA:pKa 9.3(H2O t = 25) (Uncertain)
- PSA：104.55000
- Density:1.533 g/cm3
- LogP:-1.82270
951-78-0 Relevant articles
An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir
Birmingham, William R.,Burke, Ashleigh J.,Charnock, Simon J.,Crawshaw, Rebecca,Finnigan, James D.,Green, Anthony P.,Holgate, Gregory M.,Lovelock, Sarah L.,Muldowney, Mark P.,Rowles, Ian,Thorpe, Thomas W.,Turner, Nicholas J.,Young, Carl,Zhuo, Ying,Zucoloto Da Costa, Bruna
supporting information, p. 3761 - 3765 (2022/03/15)
The Covid-19 pandemic highlights the urg...
Reactivity and DNA Damage by Independently Generated 2′-Deoxycytidin-N4-yl Radical
Peng, Haihui,Jie, Jialong,Mortimer, Ifor P.,Ma, Zehan,Su, Hongmei,Greenberg, Marc M.
, p. 14738 - 14747 (2021/09/18)
Oxidative stress produces a variety of r...
Thermodynamic Reaction Control of Nucleoside Phosphorolysis
Kaspar, Felix,Giessmann, Robert T.,Neubauer, Peter,Wagner, Anke,Gimpel, Matthias
supporting information, p. 867 - 876 (2020/01/24)
Nucleoside analogs represent a class of ...
Dehalogenation of Halogenated Nucleobases and Nucleosides by Organoselenium Compounds
Mondal, Santanu,Mugesh, Govindasamy
, p. 1773 - 1780 (2019/01/10)
Halogenated nucleosides, such as 5-iodo-...
951-78-0 Process route
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-
34279-87-3
1-(O3,O5-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-5-bromo-4-trimethylsilanyloxy-1H-pyrimidin-2-one
-
-
75-24-1
trimethylaluminum
-
-
951-78-0,63844-76-8
2'-deoxyuridine
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-
50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine
| Conditions | Yield |
|---|---|
|
With
water; ammonium chloride; triphenylphosphine;
Yield given. Multistep reaction. Yields of byproduct given;
1) THF, reflux, 12 h, 2) MeOH, reflux, 3 h;
|
-
-
54-42-2,162239-35-2
5-Iodo-2'-deoxyuridine
-
-
951-78-0,63844-76-8
2'-deoxyuridine
-
-
59-14-3,723-73-9
5-bromo-2'-deoxyuridine
| Conditions | Yield |
|---|---|
|
With
sodium bromide;
In
isopropyl alcohol;
at 0 ℃;
for 0.166667h;
UV-irradiation;
|
47 % Chromat. 39 % Chromat. |
951-78-0 Upstream products
-
109368-38-9
O5'-acetyl-2'-iodo-2'-deoxy-uridine
-
951-77-9
2'-Deoxycytidine
-
34279-87-3
1-(O3,O5-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-5-bromo-4-trimethylsilanyloxy-1H-pyrimidin-2-one
-
75-24-1
trimethylaluminum
951-78-0 Downstream products
-
958-09-8
2'-deoxy-D-adenosine
-
72045-17-1
5-<(E)-2-phenylethenyl>-2'-deoxyuridine
-
135073-79-9
5-(2,6-Dichlorobenzoyl)-2'-deoxyuridine oxime
-
101760-65-0
5-(phenylselenenyl)-2'-deoxyuridine
