Fesoterodinefumarate
- Name Fesoterodinefumarate
- CAS 286930-03-8
- Purity 99%
Product Details
Quality products?make an important contribution to long-term revenue and profitability. Purity 99% Min Fesoterodinefumarate 286930-03-8 Spot Supply with Safe Transportation
1.What is the Fesoterodinefumarate ?
(R)-Fesoterodine Fumarate is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).
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-
1391913-28-2
(R)-3-(N,N'-diisopropylamino-1-phenyl-propyl)-4-isobutyryloxy-benzoic acid
-
-
110-17-8,26099-09-2
(2E)-but-2-enedioic acid
-
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286930-03-8,1333234-73-3
fesoterodine fumarate
| Conditions | Yield |
|---|---|
|
(R)-3-(N,N'-diisopropylamino-1-phenyl-propyl)-4-isobutyryloxy-benzoic acid;
With
dimethylsulfide borane complex;
In
tetrahydrofuran;
at 10 - 25 ℃;
(2E)-but-2-enedioic acid;
In
butanone;
at 0 - 5 ℃;
for 8h;
|
60.5%
|
-
-
79-30-1
isobutyryl chloride
-
-
110-17-8,26099-09-2
(2E)-but-2-enedioic acid
-
-
207679-81-0
(R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol
-
-
286930-03-8,1333234-73-3
fesoterodine fumarate
| Conditions | Yield |
|---|---|
|
isobutyryl chloride; (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
at 5 - 20 ℃;
(2E)-but-2-enedioic acid;
In
butanone;
at 0 - 35 ℃;
for 3h;
Product distribution / selectivity;
|
85.7%
|
|
isobutyryl chloride; (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
at 0 - 5 ℃;
for 2.16667h;
(2E)-but-2-enedioic acid;
In
butanone;
at 0 - 35 ℃;
for 3h;
Product distribution / selectivity;
|
85.7%
|
|
isobutyryl chloride; (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
at 5 ℃;
(2E)-but-2-enedioic acid;
In
butanone;
at 35 ℃;
Product distribution / selectivity;
|
85.7%
|
2.What is the CAS number for Fesoterodinefumarate ?
The CAS number of Fesoterodinefumarate is 286930-03-8.
More information of Fesoterodinefumarate 286930-03-8 are:
|
CAS?Number |
286930-03-8 |
|
Melting Point |
72-78 °C |
|
Boiling Point |
518.9 °C at 760 mmHg |
|
Flash Point |
267.6 °C |
|
PSA |
124.37000 |
|
LogP |
5.09290 |
3.What are another words for Fesoterodinefumarate ?
Synonyms?for?Fesoterodinefumarate 286930-03-8:Fesoterodine;Propanoic acid, 2-methyl-, 2-((1R)-3-(bis(1-methylethyl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl ester, (2E)-2-butenedioate (1:1) (salt);2-((1R)-3-(Diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl isobutyrate;2-((1R)-3-(bis(1-methylethyl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl 2-methylpropanoate hydrogen (2E)-butenedioate (salt);(R)-Fesoterodine fumarate;
4.What is the molecular formula of Fesoterodinefumarate?
The chemical formula of ?Fesoterodinefumarate is?(x)C4 H4 O4 *C26 H37 NO3 which containing 30 Carbon atoms,41 Hydrogen atoms,4 Oxygen atoms and 1 Nitrogen atoms,and the molecular weight of??Fesoterodinefumarate?is 527.65.
5.What is Fesoterodinefumarate (286930-03-8) used for?
Fesoterodine fumarate is a new drug for the treatment of overactive bladder syndrome developed by Pfizer, which was approved by the US FDA in October 2008. Fesoterodine fumarate is a prodrug, which is rapidly hydrolyzed in blood after oral administration to 5-hydroxymethyl tolterodine (5-HMT), which is also the active metabolite of tolterodine.
InChI:InChI=1/C26H37NO3.C4H4O4/c1-18(2)26(29)30-25-13-12-21(17-28)16-24(25)23(22-10-8-7-9-11-22)14-15-27(19(3)4)20(5)6;5-3(6)1-2-4(7)8/h7-13,16,18-20,23,28H,14-15,17H2,1-6H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t23-;/m1./s1
Relevant articles related to Fesoterodinefumarate:
|
Article |
Source |
|
PROCESS FOR THE PREPARATION OF OPTICALLY PURE FESOTERODINE DERIVATIVES |
- , (2015/04/15) |
|
PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 3,3-DIPHENYLPROPYLAMINES |
- , (2013/08/15) |
6.Buy Fesoterodinefumarate with the best price .
KABILY CHEMICAL CO.,LTD.(expird) is a quality supplier of Fesoterodinefumarate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Fesoterodinefumarate 286930-03-8.